Bioinformatics is the use of mathematical and informational techniques, including statistics, to solve biological problems, usually by creating or using computer programs, mathematical models or both. One of the main areas of bioinformatics is the data mining and analysis of the data gathered by the various genome projects. Other areas are sequence alignment, protein structure prediction, systems biology, and virtual evolution. As a summary, the various genome projects produce many long lists of letters and one of the roles of bioinformatics is to attempt to determine the words, grammar, sentences and ultimately, meaning (functional significance) of those letters.

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Source: Essential-Facts.com